Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint

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Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint.

Oral submucous fibrosis (OSF) is characterized by excessive fibrosis of submucosa. The degree of vascularity in OSF has always been a matter of debate. Angiogenesis is the key mechanism involved in regeneration and repair. It also plays an important role in various pathologic conditions. Angiogenesis may contribute to the progression of fibrosis in fibrotic disorders. Inhibition of pathological...

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Oral submucous fibrosis is a chronic, insidious disease affecting the oral cavity and sometimes pharynx. Although occasionally preceded and/or associated with vesicle formation, is always associated with juxtaepithelial inflammatory reaction followed by fibro elastic changes in lamina propria with epithelial atrophy leading to stiffness of oral cavity leading to trismus and inability to eat. Al...

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ژورنال

عنوان ژورنال: The Journal of Contemporary Dental Practice

سال: 2018

ISSN: 1526-3711

DOI: 10.5005/jp-journals-10024-2244